Not sure if this fits your criteria, but Peter Chung's done some really stylish animations - e.g. the short animation Matriculated from Animatrix.
Very interesting interview here that discusses what he was trying to do with Aeon Flux, his opinion of the movie, etc.
There's also a very beautiful 4 minute animation by Antoine Antin - le Papillon. It's drawn in a Japanese brush-stroke style (using LivingCels?) - very evocative. It's not 'science' focused in the least, but it is an incredible work of art.
http://www.aantin.com/films/lepapillon.php
